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Effect of Curvature on Biofilm Growth
Ya-Wen Chang
The environment in which cells grow influences a multitude of cellular functions by providing chemical and physical signals that modulate cell behavior, dynamics, development, and eventually survival. How physical parameters of the extra-cellular environment, specifically the 3D nature influences multicellular structure developement remain poorly understood. We have developed a method to fabricate well defined curved surfaces that are sutible for growing cells. Using strcutrues such as spheres or torus, we investigate the role of curvature and geometric confinement on cell behavior at the multicell level.
Biofilm Growth on Planar and Curved Interfaces
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Soft Condensed Matter Laboratory, School of Physics, Georgia Institute of Technology
770 State Street NW, Atlanta, GA, 30332-0430, USA
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alberto.fernandez [at] physics.gatech.edu